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Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)

Funder
National Institutes of Health
Award amount
Not specified
Deadline
October 20, 2027
Eligible countries
United States

Summary

Reissue PAR-21-122. This NOFO provides funding to conduct pharmacodynamic, pharmacokinetic, and in vivo efficacy studies to demonstrate that proposed therapeutic agent(s) have sufficient biological activity to warrant further development to treat neurological or neuromuscular disorders that fall under the NINDS mission. Therapeutic agents include small molecules, biologics or biotechnology-derived products. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to advance projects to the point where they can meet the entry criteria for the Blueprint Neurotherapeutics Network or other translational programs.

Summary as listed on Grants.gov (opportunity 356953). Always read the full announcement for eligibility, limits and how to apply.

Read the full announcement on Grants.gov →

What National Institutes of Health reviewers look for

  • Importance of the research (significance and innovation), scored 1–9.
  • Rigor and feasibility of the approach, scored 1–9. Preliminary data and alternative strategies carry much of this.
  • Expertise and resources, rated sufficient or not, without a score.
  • Overall impact: the likelihood the project will have a sustained, powerful influence on its field.

Read our guide: what funded applications do →

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