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Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

Funder
National Institutes of Health
Award amount
Up to $3,000,000
Deadline
August 21, 2028
Eligible countries
United States

Summary

The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including medications and medical devices to treat co-morbid SUDs. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption. This NOFO will utilize the UG3/UH3 activity code.

Summary as listed on Grants.gov (opportunity 358937). Always read the full announcement for eligibility, limits and how to apply.

Read the full announcement on Grants.gov →

What National Institutes of Health reviewers look for

  • Importance of the research (significance and innovation), scored 1–9.
  • Rigor and feasibility of the approach, scored 1–9. Preliminary data and alternative strategies carry much of this.
  • Expertise and resources, rated sufficient or not, without a score.
  • Overall impact: the likelihood the project will have a sustained, powerful influence on its field.

Read our guide: what funded applications do →

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